COVID-19 Vaccine & Fillers: What You Should Know

Answers to your questions about the Moderna Covid vaccine and dermal fillers.

You may have seen headlines recently about late-onset swelling in people with fillers who got the Moderna COVID-19 vaccine. It’s understandable that this could raise some concern with anyone who has fillers, and I wanted to get this post out quickly so my San Francisco patients have all the facts.

A closer look at the data indicates that only 3 cases out of the 30,000 member trial group (1 out-of 10,000 cases) experienced this complication—and it’s easily remedied.

In other words, don’t worry.

Considering the statistics and the ability to rapidly treat the symptoms with antibiotics and/or oral steroids, we feel that the impact is minimal.

The Details

In general, late-onset swelling is a possible rare, adverse side-effect associated with filler treatment (prior to COVID 19 vaccine). An extremely small number of individuals experienced swelling at the site of their fillers at some point after vaccination.

While the direct cause is unknown, research points to dental cleanings (which can introduce bacteria), allergies, flu viruses, and vaccines where the body’s immune system is working to suppress infection. The body’s response to the perceived infection can be inflammation.

Antibiotics, oral steroids, and hyaluronidase can be used individually or in concert should this occur after vaccination. Your injector and your vaccinating physician should be prepared to administer these remedies.

Answers to Your Questions (FAQs)

Does it matter which vaccine I get?

So far, filler reactions were recorded only in the Moderna trial. However, physicians around the world have seen a handful of cases of filler reactions from other types of vaccines, such as flu vaccines, so it is possible that other variants of the COVID-19 vaccine could cause a reaction.

Does it matter where I get my injections?

In terms of the area of the face, no. In terms of the practice or provider, yes. To ensure your utmost safety, trust an experienced medical professional trained and prepared to diagnose and treat complications. If you develop a lump, unusual swelling, or discomfort, professionals like the injectors at Mabrie Facial Institute can take care of it right away.

Does it matter what kind of fillers I have?

The few documented instances of reaction suggest that the JUVÉDERM® Vycross gels (VOLUMA, VOLBELLA, VOLLURE) are linked to a slightly higher frequency of late-onset swelling. However, this reaction has also been seen with other hyaluronic acid fillers, such as Restylane products. All of these are reversible with injections of Hylenex®, which we always have on hand at Mabrie Facial Institute.

Does the COVID-19 vaccine react with BOTOX?

There have been no instances of late-onset swelling in patients who have been treated with BOTOX®. BOTOX is a neuromodulator, not a dermal filler, and these products feature different mechanisms of action.

If I have fillers and I get the vaccine, will I definitely experience swelling?

Statistically speaking, it is extremely unlikely that you will experience swelling. The very rare occurrence of late-onset swelling should not discourage you from filler treatment or vaccination.

The Bottom Line

We strongly encourage everyone to get vaccinated for COVID as soon as possible.

I hope that helps. If you have further questions, we’re here for you. Until then, stay positive, test negative, and always stay beautiful!

Dr. David Mabrie

Dr. David Mabrie

Facial Plastic Surgeon & Founder of Mabrie Facial Institute Dr. David Mabrie is a recognized leader, innovator, and educator in the use of dermal fillers for facial sculpting and has dedicated his practice entirely to facial rejuvenation with injectables. Years of experience led Dr. Mabrie to pioneer the Illumination 360° approach, just one of the ways Dr. Mabrie brings life to his practice’s mantra: “your face, perfected.”

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